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Luxury accommodations in Panama City

Find and book your ideal hotel in Panama City for a great vacation

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Luxury accommodations

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504 properties found in Panama City

  • Ramada Plaza By Wyndham Panama Punta Pacifica

    Ramada Plaza By Wyndham Panama Punta Pacifica

    Via Israel & Calle 71 Proximity to shopping - 300m
    "Comfortable, modern, convenient"
    Best for Business Travelers

    • On-site spa services available

    • Outdoor pool with panoramic views

    • Free daily breakfast included

    from

    US$ 74 price for 1 night
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  • Global Hotel Panama

    Global Hotel Panama

    Calle 54 Este Y Avenida Samuel Lewis, Obarrio Shopping and financial hub - 300m
    "Relaxing spa treatments"
    Best for Business Travelers

    • Fine dining restaurant and wine bar

    • Stylish event spaces for meetings

    • Rooftop outdoor swimming pool

    from

    US$ 130 price for 1 night
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  • Hotel Casa Panama

    Hotel Casa Panama

    Avenida Eloy Alfaro Y Calle 11 Close to attractions - 200m
    "Great outdoor space"
    Best for Nightlife Enthusiasts

    • Rooftop area with music events

    • Year-round outdoor swimming pool

    • Pet-friendly accommodation available

    from

    US$ 49 price for 1 night
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  • Tantalo Hotel - Kitchen - Roofbar

    Tantalo Hotel - Kitchen - Roofbar

    Avenida B Calle 8 Casco Viejo Historic Casco Viejo - 300m
    "Unique artistic experiences"
    Best for Art Lovers

    • Rooftop bar with panoramic views

    • Artfully designed suites with local artwork

    • Live music and events throughout the week

    from

    US$ 95 price for 1 night
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  • Summit Rainforest Golf Resort & All Inclusive

    Summit Rainforest Golf Resort & All Inclusive

    Ancon Close to Panama Canal - 2 km
    4.5
    1516 reviews
    Best for Nature Lovers

    • 18-hole golf course available

    • Butterfly and frog farms onsite

    • Two outdoor pools with views

    from

    US$ 36 price for 1 night
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  • Hotel La Compania Casco Antiguo

    Hotel La Compania Casco Antiguo

    Avenida A Y Calle 8, Casco Ant Close to Canal Museum - 200m
    "Spa, pool, dining"
    Best for Luxury Travelers

    • On-site spa with various treatments

    • Outdoor swimming pool with views

    • Nightclub and live music events

    from

    US$ 270 price for 1 night
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  • The Beach House

    The Beach House

    Ancon Short walk to marina - 100m
    "Comfort and relaxation guaranteed"
    Best for Leisure Travelers

    • Elegant rooms with private balconies

    • Outdoor pool open all year

    • Free Wi-Fi in all rooms

    from

    US$ 79 price for 1 night
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  • Hotel Casa Miller

    Hotel Casa Miller

    Estacion 5 De Mayo, Entre Avenida B Y Avenida Central, Panama City, Panama Cultural museum nearby - 1.5km
    "Vibrant nightlife experience"
    Best for Couples

    • Rooftop pool with views

    • Outdoor activities available

    • On-site nightclub features DJ

    from

    US$ 55 price for 1 night
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  • Ac Hotel By Marriott Panama City

    Ac Hotel By Marriott Panama City

    Calle Ricardo Arias 14, Campo Alegre Area Bancaria Close to Soho Mall - 300m
    "Perfect for relaxation"
    Best for Business Travelers

    • Infinity rooftop pool with views

    • On-site dining with local cuisine

    • 24-hour fitness center access

    from

    US$ 89 price for 1 night
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  • Hotel California Panama

    Hotel California Panama

    Calle 43 Y La Via Espana Proximity to parks - 2.3km
    "Comfortable rooms available"
    Best for Business Travelers

    • Free Wi-Fi available throughout

    • 24-hour front desk services

    • On-site fitness center access

    from

    US$ 27 price for 1 night
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  • Crowne Plaza Panama By Ihg

    Crowne Plaza Panama By Ihg

    Av. Manuel Espinosa Batista Near Financial District - 1.5km
    "Comfortable modern rooms"
    Best for Business Travelers

    • 24-hour fitness centre available

    • Outdoor swimming pool with views

    • On-site restaurant with Panamanian cuisine

    from

    US$ 93 price for 1 night
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  • Residence Inn By Marriott Panama City

    Residence Inn By Marriott Panama City

    Calle Ramon H Jurado, Calle Tomas Gabriel Duque, Edificio Pacific Center Near Multiplaza Mall - 300m
    "Family-friendly spacious rooms"
    Best for Business Travelers

    • Fully equipped kitchen in every room

    • Located in Pacific Center Complex

    • Outdoor swimming pool available year-round

    from

    US$ 174 price for 1 night
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  • Hotel Latino

    Hotel Latino

    Avenida Cuba Y Calle 36 Centrally located - 1 km
    "Modern urban retreat"
    Best for Couples

    • Rooftop swimming pool open all year

    • On-site restaurant offering local cuisine

    • Free WiFi throughout the property

    from

    US$ 24 price for 1 night
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  • Marinn Place Financial District

    Marinn Place Financial District

    Aquilino De La Guardia Y Calle 52 Centrally located - 300m
    "Modern amenities provided"
    Best for Business Travelers

    • Rooftop pool with city views

    • Versatile event venues available

    • On-site gourmet restaurant experience

    from

    US$ 65 price for 1 night
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  • Waymore Hotel Spa & Casino

    Waymore Hotel Spa & Casino

    Avenida Eusebio A. Morales Heart of Financial District - 1.5km
    "Relax and rejuvenate"
    Best for Luxury Travelers

    • Semi-Olympic outdoor pool with skyline views

    • 24-hour access to casino and dining options

    • Spa with comprehensive wellness treatments

    from

    US$ 98 price for 1 night
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  • Hotel Magnolia Boutique

    Hotel Magnolia Boutique

    Calle 8 Historic district location - 500m
    "Modern decor suites"
    Best for Couples

    • Refurbished colonial manor style

    • Terraces and shared kitchen available

    • Penthouse suite with modern decor

    from

    US$ 11 price for 1 night
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  • Marinn Tropical Vibes Hotel

    Marinn Tropical Vibes Hotel

    Ancon Near major attractions - 8.1km
    "Comfortable and modern"
    Best for Couples

    • Free private parking available

    • Air-conditioned rooms with balconies

    • 24-hour reception for convenience

    from

    US$ 91 price for 1 night
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  • Hotel Ojos Del Rio

    Hotel Ojos Del Rio

    Calle 41 Este Prime touristic area - 2.1km
    "Comfortable and modern"
    Best for Business Travelers

    • Free Wi-Fi throughout the property

    • On-site fitness center for workouts

    • 24-hour reception service available

    from

    US$ 43 price for 1 night
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  • Marriott Panama Hotel - Albrook

    Marriott Panama Hotel - Albrook

    Ancon Close to attractions - 1.5km
    "Family-friendly shopping experience"
    Best for Shopping Enthusiasts

    • Rooftop pool with stunning views

    • Adjacent to Albrook Mall

    • On-site fitness center available

    from

    US$ 203 price for 1 night
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  • Central Park Hotel & Casino

    Central Park Hotel & Casino

    Calle Miguel Brostella Heart of El Dorado - 0.5km
    "Fun, comfortable stay"
    Best for Leisure Travelers

    • Casino on-site for entertainment

    • Free Wi-Fi throughout the property

    • Complimentary welcome drink offered

    from

    US$ 51 price for 1 night
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